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Oct 11
2009

Interferon and HINI Research

Posted by Zester Hatfield in New Discoveries

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Attention-Attention-Attention All Americans Must Learn How to Protect Themselves From the Flu Viruses, Especially the HINI Virus.  Click on the link to see this historic breakthrough in what you can do personally!!

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What Interferon is and How it Works

The immune system serves as your body's natural shield against infection. A wondrously complex and multi-layered system, it was designed to protect you from potential invaders, including viruses, bacteria, and allergens. Your immune system is also able to recognize dangerous changes in your cells and destroy these potential pre-cancerous cells. Part of this protection includes the production of interferon.

Interferon is activated by the immune system when a virus attacks a cell. Interferon serves two important functions. It signals neighboring cells and triggers their resistance mechanisms, and it activates other immune cells that kill invading pathogens. Interferon is essential to the immune system and helps protect us from the daily exposure to millions of germs that can lead to serious infection.

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Interferon and HINI Research

immunology
immunology2
Scandinavian Journal of Immunology 

 

Involvement of Interleukin-2 and Interferon-Gamma in the Immune Response Induced by Influenza Virus Iscoms

 

M. VILLACRES-ERIKSSON*, M. BERGSTRÖM-MOLLAOGLU , H. KÅBERG B. MOREIN*                                      

*Swedish University of Agricultural Sciences, Department of Veterinary Microbiology, Division of Virology, Uppsala, Sweden  The National Veterinary Institute, Department of Virology, Uppsala, Sweden Correspondence to  Maria Villacres-Eriksson, Swedish Vnirersity of Agricultural Sciences, Department of Veterinary Microbiology, Division of Virology, Box 585, Blomedical Center, 75123 Uppsala, Sweden.

Copyright 1992 Blackwell Scientific Publications

ABSTRACT

Splenocytes from mice primed with influenza virus envelope proteins incorporated in iscoms, as micelles or as infectious virus, were restimulaled in vitro with the same antigen. Interleukin-2 (IL-2) and interferon-gamma (IKN-?) were assayed in the supernatants of such cultures. Influenza virus iscoms induced IL-2 and IFN-? responses in restimulation experiments that were antigen specific and significantly higher than those induced by micelles or infectious virus. Serum samples collected at the end of the experiments were analysed for the antibody response and profile. The antibody titres induced by iscoms were of a similar order of magnitude as those induced by infectious virus, and were about 18 times higher than the titres induced by micelles. In mice immunized with iscoms or infectious virus the most abundant antibodies were of the IgG1 and IgG2a, isotype, and the IgE response was low. We conclude that immunization with iscoms stimulates the Th1-like subtype of murine T lymphocytes.

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